Takeshi Takada

Education and Professional Experience

Postdoctoral Fellow University of Pittsburgh, Pittsburgh, Pennsylvania, Sept. 2002-Sept. 2003.
Associate Researcher Sankyo Co. Ltd. (Agroscience Laboratory), Japan, 1998-present. (sabbatical leave, Sep. 2002- Aug. 2003)
Ph. D. Osaka University, Osaka, Japan 1998 (Pharmaceutical Chemistry)
B.S. Osaka University, Osaka, Japan 1993 (Pharmaceutical Chemistry)

Awards and Honors

Fellowship of Japan Society for the Promotion of Sciences (JSPS) for Japanese Junior Scientists (1995-1998)



Ito, H.; Imai, C.; Takada, T.; Tanaka, H.; Ohnishi, T. “Preparation of 5-(m-cyanobenzylamino)pyrazole derivatives as fungicides for agricultural and horticultural use” PCT Int. Appl. 2002, 251 pp. (WO 0208196 A1).
Kita, Y.; Egi, M.; Takada, T.; Tohma, H. “Development of novel reactions using hypervalent iodine(III) reagents. Total synthesis of sulfur-containing pyrroloiminoquinone marine product, (±)-makaluvamine F” Synthesis, 1999, 885-897.
Kita, Y.; Egi, M.; Ohtsubo, M.; Saiki, T.; Okajima, A.; Takada, T.; Tohma, H. “Hypervalent iodine(III)-induced intramolecular cyclization reaction of substituted phenol ethers with an alkyl azido side-chain: a novel and efficient synthesis of quinone imine derivatives” Chem. Pharm. Bull., 1999, 47, 241-245.
Eichhorn, J.; Takada, T.; Kita, Y.; Zenk, M. H. “Biosynthesis of the Amaryllidaceae alkaloid galanthamine” Phytochemistry 1998, 49, 1037-1047.
Takada, T.; Arisawa, M.; Gyoten, M.; Hamada, R.; Tohma, H.; Kita, Y. “Oxidative Biaryl Coupling Reaction of Phenol Ether Derivatives Using a Hypervalent Iodine(III) Reagent” J. Org. Chem. 1998, 63, 7698-7706.
Kita, Y.; Arisawa, M.; Gyoten, M.; Nakajima, M.; Hamada, R.; Tohma, H.; Takada, T. “Oxidative intramolecular phenolic coupling reaction induced by a hypervalent iodine(III) reagent: Leading to galanthamine-type Amaryllidaceae alkaloids” J. Org. Chem. 1998, 63, 6625-6633.
Kita, Y.; Egi, M.; Ohtsubo, M.; Saiki, T.; Takada, T.; Tohma, H. ”Novel and efficient synthesis of sulfur-containing heterocycles using a hypervalent iodine(III) reagent” Chem. Commun. 1996, 2225-2226.
Kita, Y.; Takada, T.; Gyoten, M.; Tohma, H.; Zenk, M. H.; Eichhorn, J. ”An Oxidative Intramolecular Phenolic Coupling Reaction for the Synthesis of Amaryllidaceae Alkaloids Using a Hypervalent Iodine(III) Reagent” J. Org. Chem. 1996, 61, 5857-5864.
Kita, Y.; Egi, M.; Okajima, A.; Ohtsubo, M.; Takada, T.; Tohma, H. “Hypervalent iodine(III) induced intramolecular cyclization of substituted phenol ethers bearing an alkyl azido sidechain-a novel synthesis of quinone imine ketals” Chem. Commun. 1996, 1491-1492.
Kita, Y.; Gyoten, M.; Ohtsubo, M.; Tohma, H.; Takada, T. “Non-phenolic oxidative coupling of phenol ether derivatives using phenyliodine(III) bis(trifluoroacetate)” Chem. Commun. 1996, 1481-1482.
Kita, Y.; Takada, T.; Tohma, H. “Hypervalent iodine reagents in organic synthesis: nucleophilic substitution of p-substituted phenol ethers” Pure Appl. Chem. 1996, 68, 627-630.
Akai, S.; Okuno, T.; Takada, T.; Tohma, H.; Kita, Y. “Preparation of novel cyclic hypervalent iodine(III) compounds having azido, cyano, and nitrato ligands” Heterocycles 1996, 42, 47-51.
Kita, Y.; Takada, T.; Ibaraki, M.; Gyoten, M.; Mihara, S.; Fujita, S.; Tohma, H. “An Intramolecular Cyclization of Phenol Derivatives Bearing Aminoquinones Using a Hypervalent Iodine Reagent” J. Org. Chem. 1996, 61, 223-7.
Kita, Y.; Takada, T.; Mihara, S.; Whelan, B. A.; Tohma, H. “Novel and Direct Nucleophilic Sulfenylation and Thiocyanation of Phenol Ethers Using a Hypervalent Iodine(III) Reagent” J. Org. Chem. 1995, 60, 7144-8.
Kita, Y.; Takada, T.; Mihara, S.; Tohma, H. “A novel and direct sulfenylation of phenol ethers using phenyliodine(III) bis(trifluoroacetate) (PIFA) and various thiophenols” Synlett 1995, 211-12.
Kita, Y.; Tohma, H.; Takada, T.; Mitoh, S.; Fujita, S.; Gyoten, M. “A novel and direct alkyl azidation of p-alkylanisoles using phenyl iodine(III) bis(trifluoroacetate) (PIFA) and trimethylsilyl azide” Synlett 1994, 427-8.
Kita, Y.; Tohma, H.; Hatanaka, K.; Takada, T.; Fujita, S.; Mitoh, S.; Sakurai, H.; Oka, S. “Hypervalent Iodine-Induced Nucleophilic Substitution of para-Substituted Phenol Ethers. Generation of Cation Radicals as Reactive Intermediates” J. Am. Chem. Soc. 1994, 116, 3684-91.