Center Staff
Abhisek Banerjee, PhD; Research Fellow; abb34@pitt.edu
Pete Chambers, BS; Staff Chemist; pgc2+@pitt.edu
Donna Huryn, PhD; CMLD Scientific Advisor; huryn@pitt.edu
Shuli Mao, PhD; Research Fellow; shm54@pitt.edu
Jitendra Mishra, PhD; Research Fellow; shm54@pitt.edu
Stephanie Nicolay, BS; Staff Chemist; stephanienicolay@yahoo.fr
Bettina Quade, MS; Staff Chemist; @pitt.edu
Peter Wipf, PhD; Director; pwipf@pitt.edu
Michelle Woodring; Administrative Assistant; mwoodrin@pitt.edu
Li Zhang, PhD; Research Fellow;
Please direct inquiries about the Center to Pete Chambers
Each Project has two stages: research and application. At the research stage, new synthetic methodologies and chemical technologies are developed in individual research groups. At the development stage, in a centralized facility and with a dedicated staff of 2 PhD and 3 BS chemists, the Diversity-Oriented Synthesis (DOS) Core validates the protocols and devices and scales up library synthesis to access 100-10,000 single compounds per library. The DOS Core facility has convenient access to a pool of state-of-the-art automated synthesis, separation, and analysis equipment that is centrally located as part of the already well established Combinatorial Chemistry Center (CCC). This arrangement provides truly independent validation for all new methodologies and provides the Projects with immediate "real world" feedback of utility and practicality. Rigorous quality control ensures high purity samples that are shared with collaborators in the biological fields. The current arrangements include two research groups in the Departments of Pharmacology (Professor Lazo) and Pharmaceutical Sciences (Professor Day), specializing in phosphatase assays and estrogen receptor screening, respectively. Off-Campus biological collaborations currently include research groups at the NCI and UTSWMC.