Library Assays - Biological Data
Lazo/Vogt lab at the UP Medical School evaluates all UPCMLD compounds
for antiproliferative activity against human PC3 prostate cancer
This initial screening
assay is conducted in triplicate at one concentration (30 or 50 μM).
Paclitaxel is used as a positive control
compound that causes >50%
growth inhibition is evaluated to determine an IC50 value with
PC-3 cells and examined with at least two other cell lines (human
MDA-MB-231 breast cancer cells and human nonmalignant fibroblasts).
Library 1 & 2 Data
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